PCOS Challenge: The National Polycystic Ovary Syndrome Association

This study is not affiliated with PCOS Challenge, Inc.
The announcement below is being provided for informational purposes only.

Blood Pressure Research Study Seeking
Women with PCOS in Connecticut Area
*

Up to $800 Monetary Compensation Provided for Participation
See Below for Details and Eligibility Criteria

*

PCOS Blood Pressure Study - Connecticut

Study Title

Mechanisms of Hypertension in Women with Polycystic Ovary Syndrome

Why is this study being done?

  • High blood pressure and cardiovascular disease remains the greatest killer in women.
  • Women with PCOS women are at risk for both high blood pressure and cardiovascular disease because women with PCOS may be obese/overweight, have insulin resistance and/or elevations in androgens
  • Our study is designed to determine the major causes for the high blood pressure in women with PCOS
  • Both blood pressure regulation on cardiovascular disease risk are important factors that should be incorporated into medical treatment plans for women with PCOS at all ages
PCOS Blood Pressure Study
Screening includes having an oral glucose tolerance test to measure blood glucose and insulin levels. If you have impaired glucose tolerance and you are overweight or moderately obese, you are eligible to participate in the rest of the study. The study includes taking hormone medications and tests that measure blood pressure regulation.

Goals of the Study

  • Our goal is to understand the mechanisms of impaired blood regulation in women with PCOS
  • Aims of this study focus on testosterone exposure and insulin resistance (IR) as the potential causes of mild hypertension in women with PCOS that are overweight or obese
  • The study also aims to examine testosterone and IR effects in overweight and obese women that do not have PCOS
  • By understanding the role of hormones and IR in blood pressure regulation, our study hopes to improve treatment plans for women with PCOS

Eligibility Criteria

You can participate if you are a woman who meets the following criteria:

  • Age 18 to 40 years
  • Have Polycystic Ovary Syndrome OR you can participate as a Control subject if you meet the other criteria
  • Are Overweight or Obese based on your body mass index (BMI of 25–30 kg/m2):
    To calculate your BMI: https://www.nhlbi.nih.gov/health/educational/lose_wt/BMI/bmicalc.htm
  • Do not smoke
  • Do not take medications for high blood pressure, diabetes, or insulin resistance—other medications are reviewed by our study clinician before enrollment
  • Are comfortable communicating in English

Location

This study requires at least 4 in-person visits to our research laboratory in New Haven, Connecticut:

  • The John B. Pierce Laboratory, 290 Congress, New Haven, CT 06519
  • The Pierce Laboratory is right across the street from Yale University’s School of Medicine

Principal Investigators and Sub-Investigators at The John B. Pierce Laboratory and
Yale School of Medicine

  • Principal Investigator: Nina Stachenfeld, PhD
  • Sub-Investigator: Christopher L Moore, MD
  • Sub-Investigator: Lubna Pal, MBBS, FACOG, MS

Where to Go For Further Information

PCOS Study

Disclaimer*

PCOS Challenge, Inc. does not recommend or endorse any specific studies, tests, physicians, products, procedures, opinions, or other information from third parties that may be mentioned on the PCOS Challenge websites. Any such mention is for information purposes only. Any third-party services, products and websites, including those offered by affiliates, sponsors and advertisers, which may be accessed through the PCOS Challenge websites are the sole responsibility of the third party who is offering the service, product or posting the website. PCOS Challenge, Inc. makes no warranty as to the accuracy of any information on third party websites and accepts no liability for any claims, errors, and omissions or for any damage or injury to persons or property arising out of the use or operation of any services, products, materials, instructions, methods, ideas or procedures provided by third parties. Any offers, pricing, and/or promotions offered through the PCOS Challenge websites, affiliates, or any third party are subject to change without notice at the sole discretion of the party making the offer. Read Full Disclaimer.

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